Asclepius and Epione founded a dynasty of healing deities. Their daughters Hygieia, Panacea, Iaso, and Aceso personified aspects of health and healing; their sons Machaon and Podalirius became physician-heroes at Troy.
Panacea and Aceso were co-worshipped at Asclepieia as sister goddesses of healing, with Panacea representing universal cure and Aceso the process of recovery from illness.
Epione was mother to Aceso, goddess of the healing process. While Epione soothed the patient's suffering, Aceso guided the body through the stages of recovery.
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