Hera set the hundred-eyed giant Argus Panoptes to guard Io after transforming her into a heifer. When Hermes killed Argus, Hera placed his eyes upon her sacred peacock.
On Zeus's orders, Hermes slew the hundred-eyed giant Argus Panoptes who was guarding Io for Hera, earning the epithet Argeiphontes, 'Slayer of Argus.'
Argus Panoptes slew Echidna while she slept in her cave, according to Apollodorus. Hera's hundred-eyed servant caught the Mother of All Monsters off guard and ended her existence.
Hera appointed Argus Panoptes as her watchful guardian over Io. After Hermes slew him, Hera honored her servant by placing his hundred eyes upon the tail feathers of her sacred peacock.
Hermes used the Caduceus to charm all hundred of Argus Panoptes's eyes to sleep before slaying the giant, freeing Io from Hera's watchful guardian.
Hermes tells the tale of Pan and Syrinx to Argus Panoptes in Ovid's Metamorphoses, using the story and the sound of pan pipes to close the giant's hundred eyes before slaying him.
Zeus commanded Hermes to slay Argus Panoptes in order to free Io from Hera's surveillance, setting in motion the famous encounter between the trickster god and the hundred-eyed giant.
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