Hippomedon marched with his uncle (or half-brother) Adrastus as one of the Seven against Thebes. His kinship with the Argive royal house secured his place among the expedition's champions.
Hippomedon and Amphiaraus served together among the Seven against Thebes. The seer Amphiaraus had foreseen the doom of all the champions, including Hippomedon.
Hippomedon and Capaneus were fellow champions of the Seven against Thebes, both renowned for their immense physical size and ferocity in battle.
Hippomedon and Parthenopaeus fought together as champions of the Seven against Thebes. Both perished in the siege.
Hippomedon and Polynices fought together as champions of the Seven against Thebes. The expedition was mounted to restore Polynices to the Theban throne.
Hippomedon and Tydeus fought as fellow champions of the Seven against Thebes, each assigned to assault a separate gate during the siege.
The Seven against Thebes were seven champion warriors — Adrastus, Polynices, Tydeus, Capaneus, Hippomedon, Parthenopaeus, and Amphiaraus — who marched from Argos to restore Polynices to the Theban throne. All but Adrastus perished in the siege.
Hippomedon besieged Thebes as one of the Seven, attacking the Gate of Athena Onca and fighting a furious aristeia in the river Ismenus before being slain by Theban defenders.
In Aeschylus's Seven against Thebes, Hippomedon bore the image of Typhon breathing fire on his shield, a device meant to terrify the defenders at his assigned gate.
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